The problem of the “4th xenoantigen” after pig organ transplantation in non‐human primates may be overcome by expression of human “protective” proteins-Reference-Cited by-同舟云学术

The problem of the “4th xenoantigen” after pig organ transplantation in non‐human primates may be overcome by expression of human “protective” proteins

Published:2020-11 Issue:2 Volume:28 Page:
ISSN:0908-665X
Container-title:Xenotransplantation
language:en
Short-container-title:Xenotransplantation

Author:

Yamamoto Takayuki¹^ORCID,Hara Hidetaka¹^ORCID,Ayares David²,Cooper David K. C.¹^ORCID

Affiliation:

1. Xenotransplantation Program Department of Surgery University of Alabama at Birmingham Birmingham AL USA

2. Revivicor Blacksburg VA USA

Funder

Danone Institute of Canada

United Therapeutics Corporation

Publisher

Wiley

Subject

Transplantation,Immunology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/xen.12658

Reference8 articles.

1. Humoral reactivity of renal transplant‐waitlisted patients to cells from GGTA1/CMAH/B4GalNT2, and SLA Class I knockout pigs;Martens GR;Transplantation,2017

2. Evaluation of human and non‐human primate antibody binding to pig cells lacking GGTA 1/ CMAH /β4Gal NT 2 genes

3. Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

4. The final obstacle to successful pre‐clinical xenotransplantation?

5. Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein

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