Respiratory syncytial virus and other respiratory virus infections in residents of homeless shelters – King County, Washington, 2019–2021

Author:

McCulloch Denise J.12ORCID,Rogers Julia H.13ORCID,Wang Yongzhe1,Chow Eric J.1ORCID,Link Amy C.1,Wolf Caitlin R.1,Uyeki Timothy M.4,Rolfes Melissa A.4ORCID,Mosites Emily5,Sereewit Jaydee6,Duchin Jeffrey S.17,Sugg Nancy K.8,Greninger Alexander L.9,Boeckh Michael J.2,Englund Janet A.10,Shendure Jay11121314,Hughes James P.15,Starita Lea M.1112,Roychoudhury Pavitra29ORCID,Chu Helen Y.1ORCID

Affiliation:

1. Department of Medicine, Division of Allergy and Infectious Diseases University of Washington Seattle Washington USA

2. Vaccine and Infectious Disease Division Fred Hutchinson Cancer Center Seattle Washington USA

3. Department of Epidemiology University of Washington Seattle Washington USA

4. Division of Influenza National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention Atlanta Georgia USA

5. Office of the Deputy Director for Infectious Diseases Centers for Disease Control and Prevention Atlanta Georgia USA

6. Department of Laboratory Medicine and Pathology University of Washington Seattle Washington USA

7. Public Health—Seattle & King County Seattle Washington USA

8. Department of Medicine University of Washington Seattle Washington USA

9. Department of Laboratory Medicine and Pathology, Division of Virology University of Washington Seattle Washington USA

10. Seattle Children's Research Institute Seattle Washington USA

11. Department of Genome Sciences University of Washington Seattle Washington USA

12. Brotman Baty Institute for Precision Medicine Seattle Washington USA

13. Allen Discovery Center for Cell Lineage Tracing Seattle Washington USA

14. Howard Hughes Medical Institute Seattle Washington USA

15. Department of Biostatistics University of Washington Seattle Washington USA

Abstract

AbstractRespiratory syncytial virus (RSV) causes disproportionate morbidity and mortality in vulnerable populations. We tested residents of homeless shelters in Seattle, Washington for RSV in a repeated cross‐sectional study as part of community surveillance for respiratory viruses. Of 15 364 specimens tested, 35 had RSV detected, compared to 77 with influenza. The most common symptoms for both RSV and influenza were cough and rhinorrhea. Many individuals with RSV (39%) and influenza (58%) reported that their illness significantly impacted their ability to perform their regular activities. RSV and influenza demonstrated similar clinical presentations and burden of illness in vulnerable populations living in congregate settings.

Funder

Centers for Disease Control and Prevention

Gates Ventures

National Institute of Allergy and Infectious Diseases

Publisher

Wiley

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Pulmonary and Respiratory Medicine,Epidemiology

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