A bioisostere of Dimebon/Latrepirdine delays the onset and slows the progression of pathology in FUS transgenic mice

Author:

Chaprov Kirill1,Rezvykh Alexander23,Funikov Sergei2,Ivanova Tamara A.1,Lysikova Ekaterina A.1,Deykin Alexei V.45,Kukharsky Michail S.167,Yu. Aksinenko Alexey1,Bachurin Sergey O.1,Ninkina Natalia17ORCID,Buchman Vladimir L.17ORCID

Affiliation:

1. Institute of Physiologically Active Compounds Russian Academy of Science Chernogolovka Russia

2. Engelhardt Institute of Molecular Biology Russian Academy of Sciences Moscow Russia

3. Moscow Institute of Physics and Technology Dolgoprudny Russia

4. Center for Precision Genome Editing and Genetic Technologies for Biomedicine Institute of Gene Biology Russian Academy of Sciences Moscow Russia

5. Laboratory of Genome Editing for Veterinary and Biomedicine Belgorod State National Research University Belgorod region Russia

6. Pirogov Russian National Research Medical University Moscow Russia

7. School of Biosciences Cardiff University Cardiff UK

Funder

Motor Neurone Disease Association

Ministry of Science and Higher Education of the Russian Federation

Russian Foundation for Basic Research

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

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