Sustained improvement of intrinsic capacity in community‐dwelling older adults: The +AGIL Barcelona multidomain program

Author:

Ferrara Maria Cristina1,Pérez Laura Mónica2,Sole Aida Ribera23,Villa‐García Lorena2456,Ars Joan2347,Soto‐Bagaria Luis2,Bellelli Giuseppe18,Cesari Matteo9,Enfedaque María Belén10,Inzitari Marco2411

Affiliation:

1. School of Medicine and Surgery University of Milano‐Bicocca Milan Italy

2. RE‐FiT Barcelona Research Group, Vall d'Hebron Institute of Research (VHIR) and Parc Sanitari Pere Virgili Barcelona Spain

3. CIBER de Epidemiología y Salud Pública (CIBERESP) Barcelona Spain

4. Department of Medicine Universitat Autònoma de Barcelona Barcelona Spain

5. QIDA Barcelona Spain

6. Department of Public Health Mental Health and Mother‐Infant Nursing School of Nursing, Faculty of Medicine and Health Sciences University of Barcelona L'Hospitalet de Llobregat Spain

7. Aging Research Center Departament of Neurobiology Care Sciences and Society (NVS) Karolinska Institutet and Stockholm University Stockholm Sweden

8. Acute Geriatric Unit Fondazione IRCCS San Gerardo dei Tintori Hospital Monza Italy

9. Department of Clinical Sciences and Community Health University of Milan Milan Italy

10. Institut Català de la Salut, Gerència de Barcelona Barcelona Spain

11. Faculty of Health Sciences Universitat Oberta de Catalunya (UOC) Barcelona Spain

Abstract

AbstractBackgroundDifferent programs promote healthy ageing through the optimization of intrinsic capacity. However, a major challenge is to assess their sustained effects over time. +AGIL Barcelona, a consolidated multidomain program, aims to optimize older adults’ intrinsic capacity through a coordinated approach among primary care, geriatrics and community resources, in agreement with the integrated care for older people (ICOPE) guidelines. We aimed to evaluate the +AGIL Barcelona longitudinal effect on older adults’ physical performance.MethodsAll +AGIL Barcelona consecutive participants since 2016 were enrolled. After a comprehensive geriatric assessment, a tailored, multidisciplinary intervention aligned with the ICOPE guidelines is offered. It includes a 10‐week boost multicomponent exercise program, nutritional and sleep‐hygiene counselling, revision and optimization of pharmacological treatments and screening for cognitive impairment, depression and loneliness. Changes in physical performance after 3 and 6 months were assessed using mixed models including baseline frailty degree, time and all potential significant confounders.ResultsWe included 194 participants in the analysis (mean age = 81.6 [standard deviation = 5.8], 68% women). An independent, clinically and statistically significant improvement in physical performance (Short Physical Performance Battery [SPPB] test, combining gait speed, strength and balance) was found at 3 months (SPPB mean change: 1.4; 95% CI: 1.1–1.6) and 6 months (SPPB mean change: 1.1; 95% CI 0.8–1.5). Equivalent results were observed for all the SPPB sub‐tests.ConclusionsA coordinated, multidisciplinary and integrated program can benefit older adults’ intrinsic capacity. The participants’ empowerment and the connection with the available community resources are critical points for a successful intervention.

Publisher

Wiley

Subject

Internal Medicine

Reference33 articles.

1. WHO Clinical Consortium on Healthy Ageing.Report of consortium meeting 1–2 December 2016 in Geneva Switzerland(WHO/FWC/ALC/17.2).Geneva:World Health Organization;2017.

2. Frailty and Intrinsic Capacity: Two Distinct but Related Constructs

3. Frailty, a multisystem ageing syndrome

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