Risk factors associated with symptoms of temporomandibular disorders among women with hypermobile Ehlers–Danlos syndrome: Questionnaire‐based study in Finland and Sweden

Author:

Yekkalam Negin1ORCID,Novo Mehmed2ORCID,Tyrberg Mårten J.3ORCID,Sipilä Kirsi45ORCID

Affiliation:

1. Department of Odontology, Clinical Oral Physiology Umeå University Umeå Sweden

2. Department of Community Medicine and Rehabilitation, Rehabilitation Medicine Umeå University Umeå Sweden

3. Centre for Clinical Research, Västmanland Hospital Uppsala University Västerås Sweden

4. Research Unit of Population Health University of Oulu Oulu Finland

5. Medical Research Center Oulu Oulu University Hospital and University of Oulu Oulu Finland

Abstract

AbstractBackgroundGeneralized joint hypermobility as a characteristic feature of Ehlers–Danlos syndromes (EDS) is among the factors contributing to temporomandibular disorders (TMD).ObjectiveTo evaluate the prevalence of TMD symptoms and their risk factors among women born in Sweden or Finland who were 27‐ to 78‐year‐olds with diagnosed hypermobile EDS (hEDS).MethodsA cohort of women with confirmed hEDS (n = 185) was constructed from the members of the National EDS Associations in both countries. Based on questionnaire data, frequency of independent variables in terms of socio‐demographic, general health and oral health‐related factors, comorbid symptoms and psychological distress for self‐reported TMD symptoms as the dependent variables, were calculated first. Prevalence ratios (PR) and their 95% confidence interval (95% CI) were estimated for the association between independent and dependent variables.ResultsNearly all participants reported TMD symptoms (98%) with TMD pain (95%), TMJ clicking (90%) and jaw fatigue (80%) as the most common symptoms and TMJ crepitation (63%) and luxation (44%) as the least common symptoms. Risk factors for TMD among 27‐ to 50‐year‐olds participants were Finland as a country of birth, living alone and self‐reported worst pain in the body (not the joints). The respective risk factors among the 51‐ to 78‐year‐olds were Finland as a country of birth, family history of EDS, tinnitus and regularly taking contraceptives.ConclusionsAmong adult women with confirmed hEDS, socio‐demographic and health‐related factors and comorbid symptoms were significantly associated with TMD but with differences regarding age group. Therefore, management of TMD requires a multidisciplinary approach among the affected.

Publisher

Wiley

Reference51 articles.

1. Research diagnostic criteria for temporomandibular disorders: review, criteria, examinations and specifications, critique;Dworkin SF;J Craniomandib Disord,1992

2. National Institute of Dental and Craniofacial Research.Facial pain.https://www.nidcr.nih.gov/research/data‐statistics/facial‐pain. Accessed May 1 2023.

3. Physical therapy for patients with TMD: a descriptive study of treatment, disability, and health status;Di Fabio RP;J Orofac Pain,1998

4. Prevalence of temporomandibular joint disorders: a systematic review and meta-analysis

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