Structural insight into proteolytic activation and regulation of the complement system

Author:

Schatz-Jakobsen Janus A.1,Pedersen Dennis V.1,Andersen Gregers R.1

Affiliation:

1. Department of Molecular Biology and Genetics; Aarhus University; Aarhus Denmark

Funder

Lundbeck Foundation LUNA Nanomedicine Centre

Novo Nordisk Foundation through a Hallas-Møller Fellowship

Danish Research Council for Nature and Universe

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference136 articles.

1. Complement activation, regulation, and molecular basis for complement-related diseases;Bajic;EMBO J,2015

2. Complement is activated by IgG hexamers assembled at the cell surface;Diebolder;Science,2014

3. Structural basis of complement membrane attack complex formation;Serna;Nat Commun,2016

4. Heterogeneous MAC initiator and pore structures in a lipid bilayer by phase-plate cryo-electron tomography;Sharp;Cell Rep,2016

5. Complement activation by ligand-driven juxtaposition of discrete pattern recognition complexes;Degn;Proc Natl Acad Sci USA,2014

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