Overlap of obsessive compulsive and psychosis risk symptoms in a specialized clinic

Author:

West Michelle L.1ORCID,Green James234ORCID,Barber Madison E.15,Sharif Shadi1ORCID,Lisowski Victoria234,Friedman‐Yakoobian Michelle2346

Affiliation:

1. Department of Psychiatry University of Colorado School of Medicine, Anschutz Medical Campus Aurora Colorado USA

2. Department of Psychiatry Beth Israel Deaconess Medical Center Boston Massachusetts USA

3. Department of Mental Health Massachusetts Mental Health Center Boston Massachusetts USA

4. Brookline Center for Community Mental Health Brookline Massachusetts USA

5. Metropolitan State University of Denver Denver Colorado USA

6. Department of Psychiatry Harvard Medical School Boston Massachusetts USA

Abstract

AbstractAimPsychotic disorders and obsessive‐compulsive disorder (OCD) commonly co‐occur. Likewise, subthreshold psychosis symptoms (clinical high risk for psychosis; CHR) and obsessive compulsive symptoms (OCS) often overlap and may be difficult to differentiate. This study aimed to replicate research investigating the prevalence of OCD in a CHR clinic sample, validate and investigate factor structure of a self‐report OCS measure in a CHR sample, explore how OCS may relate to CHR and co‐occurring symptoms, and investigate whether real‐world CHR treatment improves OCS and CHR symptoms.MethodThis study analysed archival clinical data from baseline and 6‐month follow‐up assessments collected by a specialist outpatient CHR clinic. Data included assessments of CHR symptoms, OCS, and clinician‐rated diagnosis. Exploratory factor analysis examined the OCS measure.ResultsWithin this CHR clinic sample, 13.5% experienced co‐morbid OCD. The self‐report OCS measure had two factors: (1) checking and counting behaviours and (2) intrusive thoughts and images of harm/guilt. The checking and counting factor correlated with depression and social anxiety. The intrusive thoughts and images of harm/guilt factor significantly correlated with unusual thought content and social anxiety. Between baseline to 6‐month follow‐up, clients exhibited CHR symptom improvement regardless of OCD diagnosis. However, OCS did not change.ConclusionsThese findings support validity of a self‐report OCS measure in a CHR clinic sample and that types of OCS experiences may exhibit different clinical patterns. Additionally, it appears that individuals with comorbid OCD responded similarly to CHR treatment compared to those without OCD.

Funder

Sidney R. Baer, Jr. Foundation

Publisher

Wiley

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