2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice-Reference-Cited by-同舟云学术

2-Methoxyestradiol confers neuroprotection and inhibits a maladaptive HIF-1α response after traumatic brain injury in mice

Published:2014-04-02 Issue:6 Volume:129 Page:940-954
ISSN:0022-3042
Container-title:Journal of Neurochemistry
language:en
Short-container-title:J. Neurochem.

Author:

Schaible Eva-Verena¹,Windschügl Julia¹,Bobkiewicz Wiesia¹,Kaburov Yordan¹,Dangel Larissa¹²,Krämer Tobias¹,Huang Changsheng¹,Sebastiani Anne¹,Luh Clara¹,Werner Christian¹²,Engelhard Kristin¹²,Thal Serge C.¹,Schäfer Michael K.E.¹²

Affiliation:

1. Department of Anesthesiology; University Medical Center; Johannes Gutenberg-University; Mainz Germany

2. Focus Program Translational Neuroscience (FTN); Johannes Gutenberg-University; Mainz Germany

Funder

Johannes Gutenberg-University Mainz

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/jnc.12708/fullpdf

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3. Prosurvival and prodeath effects of hypoxia-inducible factor-1α stabilization in a murine hippocampal cell line;Aminova;J. Biol. Chem.,2005

4. Antioxidants, HIF prolyl hydroxylase inhibitors or short interfering RNAs to BNIP3 or PUMA, can prevent prodeath effects of the transcriptional activator, HIF-1α, in a mouse hippocampal neuronal line;Aminova;Antioxid. Redox Signal.,2008

5. Phosphatidylinositol 3-kinase/akt signaling is neither required for hypoxic stabilization of HIF-1α nor sufficient for HIF-1-dependent target gene transcription;Arsham;J. Biol. Chem.,2002

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