A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds

Author:

De Vleeschauwer A. R.1,Lefebvre D. J.1,Willems T.1,Paul G.2,Billiet A.3,Murao L. E.3,Neyts J.34,Goris N.3,De Clercq K.1

Affiliation:

1. Unit of Vesicular and Exotic Diseases; OD Viral Diseases; CODA-CERVA; Veterinary and Agrochemical Research Centre; Brussel Belgium

2. MSD Animal Health; Intervet International GmbH; Köln Germany

3. Aratana Therapeutics NV; Leuven Belgium

4. Department of Microbiology and Immunology; Rega Institute for Medical Research; Katholieke Universiteit Leuven; Leuven Belgium

Funder

Belgian Federal Public Service of Health

Food Chain Safety and Environment

Seventh Framework Programme

FMD-DISCONVAC

EUVIRNA

Publisher

Wiley

Subject

General Veterinary,General Immunology and Microbiology,General Medicine

Reference33 articles.

1. A comparison of different methods of inoculating guinea pigs with the virus of foot-and-mouth disease;Aramburu;J. Comp. Pathol. Ther.,1949

2. Oil-adjuvant vaccine against foot-and-mouth disease;Bahnemann;Boletin del Centro Panamericano Fiebre Aftosa.,1987

3. The history of research in foot-and-mouth disease;Brown;Virus Res.,2003

4. Evaluation of Lassa antiviral compound ST-193 in a guinea pig model;Cashman;Antiviral Res.,2011

5. Council Directive 2003/85/EC http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2003:306:0001:0087:EN:PDF

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