Pro-survival redox signalling in progesterone-mediated retinal neuroprotection

Author:

Ruiz Lopez Ana M.1,Roche Sarah L.1,Wyse Jackson Alice C.1,Moloney Jennifer N.1,Byrne Ashleigh M.1,Cotter Thomas G.1

Affiliation:

1. Cell Development and Disease Laboratory; Biochemistry Department; Biosciences Institute; University College Cork; Cork Ireland

Funder

Science Foundation Ireland

Fighting Blindness Ireland

Publisher

Wiley

Subject

General Neuroscience

Reference44 articles.

1. Functional and structural modifications during retinal degeneration in the rd10 mouse;Barhoum;Neuroscience,2008

2. Rod and cone photoreceptor cells produce ROS in response to stress in a live retinal explant system;Bhatt;Mol. Vis.,2010

3. The synthetic progestin norgestrel acts to increase LIF levels in the rd10 mouse model of retinitis pigmentosa;Byrne;Mol. Vis.,2016a

4. The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration;Byrne;Redox. Biol.,2016b

5. Oxidative stress induces caspase-independent retinal apoptosis in vitro;Carmody;Cell Death Differ.,2007

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