Periodontal conditions and association of periodontitis with oral‐health‐related quality of life in patients experiencing different episodes of bipolar disorder compared with healthy controls

Abstract

AbstractAimThe aim of the present cross‐sectional study was to evaluate periodontal conditions and the association of periodontitis with oral‐health‐related quality of life (OHRQoL) in patients with a history of bipolar disorder.Materials and MethodsA total of 160 participants were recruited in four groups for the study: 40 patients with euthymic episodes, 40 patients with depression, 40 patients with manic episodes and 40 systemically healthy individuals. Clinical periodontal parameters were recorded. Oral Health Impact Profile (OHIP‐14) was used to measure the impact of oral health on the quality of life.ResultsBipolar disorder groups exhibited generally higher clinical parameters compared with the control group (p < .05). OHIP‐14 total score (β = 3.32, 95% confidence interval [CI]: 0.08–6.56, p = .044), functional limitation (β = .89, 95% CI: 0.27–1.49, p = .005) and physical pain (β = .64, 95% CI: 0.01–1.27, p = .046) were associated with bipolar depression episodes. Psychological discomfort was associated with the presence of generalized periodontitis (β = .76, 95% CI: 0.01–1.51, p = .047) and psychological disability was associated with the presence of stage III–IV (β = .83, 95% CI: 0.07–1.59, p = .033) and generalized (β = .75, 95% CI: 0.07–1.42, p = .029) periodontitis.ConclusionsAccording to this study, a history of bipolar disorder episodes (exposure) may be associated with increased prevalence and severity of periodontitis and related reported OHRQoL impacts (outcomes). Bipolar depression episodes had a higher impact on OHRQoL than other bipolar episodes.