Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA

Author:

Angoa-Pérez Mariana12,Kane Michael J.12,Briggs Denise I.12,Francescutti Dina M.12,Sykes Catherine E.12,Shah Mrudang M.13,Thomas David M.14,Kuhn Donald M.12

Affiliation:

1. Research & Development Service; John D. Dingell VA Medical Center; Detroit Michigan USA

2. Department of Psychiatry & Behavioral Neurosciences; Wayne State University School of Medicine; Detroit Michigan USA

3. Department of Pharmaceutical Sciences; Eugene Applebaum College of Pharmacy and Health Sciences; Wayne State University; Detroit Michigan USA

4. Department of Biomedical Sciences; Oakland University William Beaumont School of Medicine; Rochester Michigan USA

Funder

National Institute on Drug Abuse

Department of Veterans Affairs

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

Reference56 articles.

1. Mephedrone, an abused psychoactive component of ‘bath salts’ and methamphetamine congener, does not cause neurotoxicity to dopamine nerve endings of the striatum;Angoa-Perez;J. Neurochem.,2012

2. The designer methcathinone analogs, mephedrone and methylone, are substrates for monoamine transporters in brain tissue;Baumann;Neuropsychopharmacology,2012

3. Hyperthermia and multiorgan failure after abuse of ‘bath salts’ containing 3,4-methylenedioxypyrovalerone;Borek;Ann. Emerg. Med.,2012

4. Nomifensine: a review of its pharmacological properties and therapeutic efficacy in depressive illness;Brogden;Drugs,1979

5. Instability of the ecstasy market and a new kid on the block: mephedrone;Brunt;J. Psychopharmacol.,2011

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