Susceptibility to 6-MP toxicity conferred by aNUDT15variant in Japanese children with acute lymphoblastic leukaemia-Reference-Cited by-同舟云学术

Susceptibility to 6-MP toxicity conferred by aNUDT15variant in Japanese children with acute lymphoblastic leukaemia

Published:2015-06-02 Issue:1 Volume:171 Page:109-115
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Tanaka Yoichi¹,Kato Motohiro²,Hasegawa Daisuke³,Urayama Kevin Y.⁴⁵,Nakadate Hisaya⁶,Kondoh Kensuke⁷,Nakamura Kozue⁸,Koh Katsuyoshi⁹,Komiyama Takako¹,Manabe Atsushi³

Affiliation:

1. Department of Clinical Pharmacy; Centre for Clinical Pharmacy and Sciences; School of Pharmacy; Kitasato University; Tokyo Japan

2. Department of Paediatrics; The University of Tokyo; Tokyo Japan

3. Department of Paediatrics; St. Luke's International Hospital; Tokyo Japan

4. Department of Human Genetics and Disease Diversity; Tokyo Medical and Dental University; Tokyo Japan

5. Centre for Clinical Epidemiology; St. Luke's Life Science Institute; Tokyo Japan

6. Department of General Paediatrics & Interdisciplinary Medicine; National Centre for Child Health and Development; Tokyo Japan

7. Department of Paediatrics; St. Marianna University School of Medicine; Kanagawa Japan

8. Department of Paediatrics; Teikyo University Hospital; Tokyo Japan

9. Department of Haematology/Oncology; Saitama Children's Medical Centre; Saitama Japan

Publisher

Wiley

Subject

Hematology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bjh.13518/fullpdf

Reference20 articles.

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2. Allelotype frequency of the thiopurine methyltransferase (TPMT) gene in Japanese;Kumagai;Pharmacogenetics,2001

3. Variable mercaptopurine metabolism and treatment outcome in childhood lymphoblastic leukemia;Lennard;Journal of Clinical Oncology,1989

4. Significance of the complete clearance of peripheral blasts after 7 days of prednisolone treatment in children with acute lymphoblastic leukemia: the Tokyo Children's Cancer Study Group Study L99-15;Manabe;Haematologica,2008

5. Methylated metabolites of 6-mercaptopurine are associated with hepatotoxicity;Nygaard;Clinical Pharmacology and Therapeutics,2004

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