Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength

Author:

Tarshish Elizabeth1,Hermoni Karin2,Muizzuddin Neelam3

Affiliation:

1. Lycored Ltd Beer Sheva Israel

2. Lycored CORP Secaucus New Jersey USA

3. Skin Clinical Research Consultants LLC Bethpage New York USA

Abstract

AbstractIntroductionImprovement of skin barrier strength could lead to healthy and youthful appearance. “Beauty inside‐out” approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population.MethodA panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use.ResultsResults indicated a statistically significant improvement (p < 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer.ConclusionBased on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.

Publisher

Wiley

Subject

Dermatology

Reference62 articles.

1. The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease‐affected skin;Del Rosso JQ;J Clin Aesthet Dermatol,2011

2. Barrier function regulates epidermal lipid and DNA synthesis

3. Water Distribution and Related Morphology in Human Stratum Corneum at Different Hydration Levels

4. The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

5. Understanding the epidermal barrier in healthy and compromised skin: clinically relevant information for the dermatology practitioner proceedings of an expert panel roundtable meeting;Del Rosso J;Supp J Clin Aesthetic Derm,2016

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