Influence of CYP2D6 and β2-adrenergic receptor gene polymorphisms on the hemodynamic response to propranolol in Chinese Han patients with cirrhosis

Author:

Zhang Feng1,Duan Xuhong1,Zhang Ming1,Li Zhenlei1,He Qibin1,Wang Yi1,Miao Chengcheng1,Zhong Wenqi1,Zou Xiaoping1,Zhuge Yuzheng1

Affiliation:

1. Department of Gastroenterology; Affiliated Drum Tower Hospital of Nanjing University Medical School; Nanjing China

Funder

Medical Science and technology development Foundation, Nanjing Department of Health, China

Publisher

Wiley

Subject

Gastroenterology,Hepatology

Reference25 articles.

1. Liver cirrhosis;Tsochatzis;Lancet,2014

2. Prognostic value of acute hemodynamic response to i.v. propranolol in patients with cirrhosis and portal hypertension;La Mura;J. Hepatol.,2009

3. Influence of beta-2 adrenergic receptor gene polymorphism on the hemodynamic response to propranolol in patients with cirrhosis;Turnes;Hepatology,2006

4. Impact of CYP2D6 poor metabolizer phenotype on propranolol pharmacokinetics and response;Sowinski;Pharmacotherapy,1997

5. Propranolol disposition in Chinese subjects of different CYP2D6 genotypes;Lai;Clin. Pharmacol. Ther.,1995

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