Evaluation of real-life dosing of oral medicines with respect to fluid and food intake in a Dutch-speaking population

Author:

Hens B.12,Van Den Abeele J.1,Rubbens J.1,Keirsebilck M.1,Roelens J.1,Schreurs C.1,Verheyen K.1,Casteels M.3,Laekeman G.3,Augustijns P.1

Affiliation:

1. Drug Delivery and Disposition; KU Leuven, O&N2; Leuven Belgium

2. College of Pharmacy; University of Michigan; Ann Arbor MI USA

3. Clinical Pharmacology and Pharmacotherapy; KU Leuven, O&N2; Leuven Belgium

Funder

Jari Rubbens acknowledges the Research Foundation Flanders (FWO; PhD fellowship)

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference37 articles.

1. U.S. Food and Drug Administration Drug Innovation - Novel Drug Approvals for 2015 [Internet] http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DrugInnovation/ucm430302.htm

2. http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2010/01/WC500070039.pdf%5D

3. http://www.fda.gov/downloads/RegulatoryInformation/Guidances/UCM126833.pdf%5D

4. http://www.orbitoproject.eu/sites/default/files/documents/5.%20OSD%20Yamashita%20Shinji.pdf

5. Mechanistic investigation of food effect on disintegration and dissolution of BCS class III compound solid formulations: the importance of viscosity;Radwan;Biopharm Drug Dispos,2012

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