Procoagulant changes in fibrin clot structure in patients with cirrhosis are associated with oxidative modifications of fibrinogen

Author:

Hugenholtz G. C. G.1,Macrae F.2,Adelmeijer J.1,Dulfer S.1,Porte R. J.3,Lisman T.13,Ariëns R. A. S.2

Affiliation:

1. Surgical Research Laboratory; Department of Surgery; University of Groningen; University Medical Center Groningen; Groningen the Netherlands

2. Thrombosis Research Group; Division of Cardiovascular and Diabetes Research; Leeds Institute of Genetics, Health and Therapeutics; University of Leeds; Leeds UK

3. Section of Hepatobiliary Surgery and Liver Transplantation; Department of Surgery; University of Groningen; University Medical Center Groningen; Groningen the Netherlands

Funder

British Heart Foundation

Publisher

Wiley

Subject

Hematology

Reference59 articles.

1. Rebalanced hemostasis in patients with liver disease: evidence and clinical consequences;Lisman;Blood,2010

2. The coagulopathy of chronic liver disease;Tripodi;N Engl J Med,2011

3. Coagulation in Liver Disease Group. Hypercoagulation and thrombophilia in liver disease;Northup;J Thromb Haemost,2008

4. Parenchymal extinction: coagulation and hepatic fibrogenesis;Anstee;Clin Liver Dis,2009

5. Coagulation status modulates murine hepatic fibrogenesis: implications for the development of novel therapies;Anstee;J Thromb Haemost,2008

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