Pronounced antiepileptic activity of the subtype-selective GABAA -positive allosteric modulator PF-06372865 in the GAERS absence epilepsy model
Author:
Affiliation:
1. SynapCell SAS; Saint Ismier France
2. Neuroscience Research Unit; Pfizer Inc; Cambridge Massachusetts
3. Early Clinical Development; Pfizer Inc; Granta Park, Cambridge UK
Funder
Pfizer
Publisher
Wiley
Subject
Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/cns.13046/fullpdf
Reference33 articles.
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2. Pharmacology of absence epilepsy;Manning;Trends Pharmacol Sci,2003
3. When antiepileptic drugs aggravate epilepsy;Genton;Brain Dev,2000
4. The electroencephalogram in epilepsy and in conditions of impaired consciousness;Gibbs;Arch Neurol Psychiatr,1935
5. The genetic absence epilepsy rat from Strasbourg as a model to decipher the neuronal and network mechanisms of generalized idiopathic epilepsies;Depaulis;J Neurosci Methods,2016
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