Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas-Reference-Cited by-同舟云学术

Combinations of four or more CpGs methylation present equivalent predictive value for MGMT expression and temozolomide therapeutic prognosis in gliomas

Published:2018-08-16 Issue:3 Volume:25 Page:314-322
ISSN:1755-5930
Container-title:CNS Neuroscience & Therapeutics
language:en
Short-container-title:CNS Neurosci Ther

Author:

Chai Rui‐Chao¹²,Zhang Ke‐Nan¹²³,Liu Yu‐Qing¹²,Wu Fan¹²,Zhao Zheng¹²,Wang Kuan‐Yu¹²³,Jiang Tao¹²³^ORCID,Wang Yong‐Zhi¹²³^ORCID

Affiliation:

1. Department of Molecular NeuropathologyBeijing Neurosurgical Institute, Capital Medical University Beijing China

2. Chinese Glioma Genome Atlas (CGGA) Beijing China

3. Department of Neurosurgery Beijing Tiantan Hospital, Capital Medical University Beijing China

Funder

National Natural Science Foundation of China

Beijing Nova Program

Publisher

Wiley

Subject

Pharmacology (medical),Physiology (medical),Psychiatry and Mental health,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cns.13040

Reference34 articles.

1. MGMT: its role in cancer aetiology and cancer therapeutics

2. Inactivation of the DNA-Repair GeneMGMTand the Clinical Response of Gliomas to Alkylating Agents

3. Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene

4. Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide

5. MGMTGene Silencing and Benefit from Temozolomide in Glioblastoma

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Accurate and rapid molecular subgrouping of high-grade glioma via deep learning-assisted label-free fiber-optic Raman spectroscopy;PNAS Nexus;2024-05-27

2. A systematic review of high impact CpG sites and regions for MGMT methylation in glioblastoma [A systematic review of MGMT methylation in GBM];BMC Neurology;2024-03-23

3. A Systematic Review of High Impact CpG Sites and Regions for MGMT Methylation in Glioblastoma [A Systematic Review of MGMT Methylation in GBM];2023-10-11

4. MGMT methylation pattern of long-term and short-term survivors of glioblastoma reveals CpGs of the enhancer region to be of high prognostic value;Acta Neuropathologica Communications;2023-08-28

5. Molecular pathology and clinical implications of diffuse glioma;Chinese Medical Journal;2022-12-20