Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver-Reference-Cited by-同舟云学术

Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver

Published:2018-02-27 Issue:3 Volume:17 Page:e12742
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Whitton Holly¹,Singh Larry N.²,Patrick Marissa A.³,Price Andrew J.³,Osorio Fernando G.⁴,López-Otín Carlos⁴⁵,Bochkis Irina M.¹³^ORCID

Affiliation:

1. Broad Institute of MIT and Harvard; Cambridge MA USA

2. Center for Mitochondrial and Epigenomic Medicine; Children's Hospital of Philadelphia; Philadelphia PA USA

3. Department of Pharmacology; University of Virginia; Charlottesville VA USA

4. Departamento de Bioquímica y Biología Molecular; Facultad de Medicina; Instituto Universitario de Oncología (IUOPA); Universidad de Oviedo; Oviedo Spain

5. Centro de Investigación Biomédica en Red de Cáncer; Madrid Spain

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

European Union (ERC Advanced Grant, DeAge)

Ministerio de Economía y Competitividad

Fundación Bancaria Caja de Ahorros de Asturias

Publisher

Wiley

Subject

Cell Biology,Ageing

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/acel.12742/fullpdf

Reference52 articles.

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2. Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina-associated domains;Berman;Nature Genetics,2012

3. Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver;Bochkis;Cell Reports,2014

4. Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress;Bochkis;Nature Medicine,2008

5. Foxa2-dependent hepatic gene regulatory networks depend on physiological state;Bochkis;Physiological Genomics,2009

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