Expression of p16INK 4a is a biomarker of chondrocyte aging but does not cause osteoarthritis

Author:

Diekman Brian O.123ORCID,Sessions Garrett A.2ORCID,Collins John A.2ORCID,Knecht Anne K.4,Strum Susan L.4,Mitin Natalia K.4,Carlson Cathy S.5ORCID,Loeser Richard F.26ORCID,Sharpless Norman E.178ORCID

Affiliation:

1. Lineberger Comprehensive Cancer Center; University of North Carolina School of Medicine; Chapel Hill North Carolina

2. Thurston Arthritis Research Center; University of North Carolina School of Medicine; Chapel Hill North Carolina

3. Department of Biomedical Engineering; University of North Carolina, Chapel Hill, NC; North Carolina State University; Raleigh North Carolina

4. HealthSpan Diagnostics LLC; Research Triangle Park North Carolina

5. Department of Veterinary Clinical Sciences; University of Minnesota; St. Paul Minnesota

6. Division of Rheumatology, Allergy, and Immunology; University of North Carolina School of Medicine; Chapel Hill North Carolina

7. Departments of Medicine and Genetics; University of North Carolina School of Medicine; Chapel Hill North Carolina

8. The National Cancer Institute; Bethesda Maryland

Funder

National Institute on Aging

Arthritis National Research Foundation

American Federation for Aging Research

Publisher

Wiley

Subject

Cell Biology,Aging

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