Metformin directly targets the H3K27me3 demethylase KDM6A/UTX-Reference-Cited by-同舟云学术

Metformin directly targets the H3K27me3 demethylase KDM6A/UTX

Published:2018-05-08 Issue:4 Volume:17 Page:e12772
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Cuyàs Elisabet¹²^ORCID,Verdura Sara¹²^ORCID,Llorach-Pares Laura³^ORCID,Fernández-Arroyo Salvador⁴^ORCID,Luciano-Mateo Fedra⁴^ORCID,Cabré Noemí⁴^ORCID,Stursa Jan⁵⁶,Werner Lukas⁵⁶,Martin-Castillo Begoña⁷,Viollet Benoit⁸⁹¹⁰^ORCID,Neuzil Jiri⁶¹¹^ORCID,Joven Jorge⁴^ORCID,Nonell-Canals Alfons³,Sanchez-Martinez Melchor³^ORCID,Menendez Javier A.¹²^ORCID

Affiliation:

1. ProCURE (Program Against Cancer Therapeutic Resistance); Metabolism & Cancer Group; Catalan Institute of Oncology; Girona Catalonia Spain

2. Girona Biomedical Research Institute (IDIBGI); Girona Spain

3. Mind the Byte; Barcelona Spain

4. Unitat de Recerca Biomèdica; Hospital Universitari de Sant Joan; IISPV; Rovira i Virgili University; Reus Spain

5. Institute of Chemical Technology; Prague Czech Republic

6. Institute of Biotechnology; Czech Academy of Sciences; Prague-West Czech Republic

7. Unit of Clinical Research; Catalan Institute of Oncology; Girona Spain

8. INSERM U1016; Institut Cochin; Paris France

9. CNRS UMR 8104; Paris France

10. Université Paris Descartes; Sorbonne Paris Cité; Paris France

11. School of Medical Science; Menzies Health Institute Queensland; Griffith University; Southport Queensland Australia

Funder

Ministerio de Ciencia e Innovación

Plan Nacional de I+D+I, Spain

Agència de Gestió d’Ajuts Universitaris i de Recerca

Departament d'Economia i Coneixement, Catalonia, Spain

Czech Health Council Foundation

Ministerio de Sanidad y Consumo

Fondo de Investigación Sanitaria (FIS), Spain

Roche Pharma (Spain)

Astellas Pharma (Spain)

Armangué family (Girona, Catalonia) to the Metabolism and Cancer Group (Girona Biomedical Research Institute)

Publisher

Wiley

Subject

Cell Biology,Aging

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/acel.12772/fullpdf

Reference66 articles.

1. Metformin as a tool to target aging;Barzilai;Cell Metabolism,2016

2. Epigenetic regulation of ageing: Linking environmental inputs to genomic stability;Benayoun;Nature Reviews Molecular Cell Biology,2015

3. The aging epigenome;Booth;Molecular Cell,2016

4. Mitochondrial targeting of metformin enhances its activity against pancreatic cancer;Boukalova;Molecular Cancer Therapeutics,2016

5. Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria;Bridges;The Biochemical Journal,2014

Cited by 64 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The direct targets of metformin in diabetes and beyond;Trends in Endocrinology & Metabolism;2024-09

2. GPRC6A is a Potential Therapeutic Target for Metformin Regulation of Glucose Homeostasis in Mice;2024-08-20

3. Roles of Lysine Methylation in Glucose and Lipid Metabolism: Functions, Regulatory Mechanisms, and Therapeutic Implications;Biomolecules;2024-07-19

4. Cellular senescence in metastatic prostate cancer: A therapeutic opportunity or challenge (Review);Molecular Medicine Reports;2024-07-08

5. KDM6A–SND1 interaction maintains genomic stability by protecting the nascent DNA and contributes to cancer chemoresistance;Nucleic Acids Research;2024-06-08