Characteristics of intussusception among children in Hokkaido, Japan, during the pre‐ and post‐rotavirus vaccine eras (2007–2016)

Author:

Fukuda Yuya1ORCID,Akane Yusuke1,Honjo Saho1,Kawasaki Yukihiko1,Tsutsumi Hiroyuki1,Tsugawa Takeshi1ORCID

Affiliation:

1. Department of Pediatrics Sapporo Medical University School of Medicine Sapporo Japan

Abstract

AbstractAimTo analyse the epidemiology of intussusception in Hokkaido Prefecture, Japan during a 10‐year period spanning the introduction of the rotavirus (RV) vaccine (2007–2016).MethodsUsing a standard questionnaire, a retrospective surveillance was conducted across 17 hospitals with paediatric beds in Hokkaido Prefecture. We compared the data between the pre‐vaccine era (2007–2011) and post‐vaccine era (2012–2016).ResultsIn total, 208 and 110 intussusception cases were in the pre‐ and post‐vaccine eras, respectively. A significant reduction of the intussusception incidence in children aged <1 year was observed from the pre‐ to the post‐vaccine era (102.4–56.5 per 100 000 infants; incidence rate ratio, 0.55; p = 0.004). There was a relatively high‐positive RV antigen detection rate (29.4%, 5/17) during the RV epidemic period in Japan (March–May) in the pre‐vaccine era. None of the intussusception cases in the 31 patients with a history of RV vaccination occurred within 1 month after the administration of an RV vaccine dose.ConclusionsThe incidence of intussusception in children aged <1 year decreased significantly after RV vaccine introduction in Japan. Another survey is needed to determine how the incidence of intussusception has changed further since the introduction of routine RV vaccination in 2020.

Publisher

Wiley

Subject

General Medicine,Pediatrics, Perinatology and Child Health

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3