N‐acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double‐blind controlled trial in healthy subjects-Reference-Cited by-同舟云学术

N‐acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double‐blind controlled trial in healthy subjects

Published:2019-01-02 Issue:3 Volume:33 Page:303-311
ISSN:0767-3981
Container-title:Fundamental & Clinical Pharmacology
language:en
Short-container-title:Fundam Clin Pharmacol

Author:

Pickering Gisèle¹²,Macian Nicolas¹^ORCID,Papet Isabelle³,Dualé Christian¹²,Coudert Catherine⁴,Pereira Bruno⁵

Affiliation:

1. Centre de Pharmacologie Clinique CIC Inserm 1405 CHU Clermont‐Ferrand Clermont–Ferrand Auvergne 63000 France

2. Inserm 1107 Université Clermont Auvergne Neurodol Clermont–Ferrand Auvergne 63000 France

3. INRA UNH Unité de Nutrition Humaine CRNH Université Clermont Auvergne Clermont‐Ferrand Auvergne 63000 France

4. Pharmacie centrale CHU Clermont‐Ferrand Clermont–Ferrand Auvergne 63000 France

5. DRCI CHU Clermont‐Ferrand Clermont‐Ferrand Auvergne 63000 France

Funder

University Hospital of Clermont-Ferrand

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/fcp.12437

Reference48 articles.

1. The modern pharmacology of paracetamol: therapeutic actions, mechanism of action, metabolism, toxicity and recent pharmacological findings

2. Paracetamol metabolism and related genetic differences

3. Acetaminophen Metabolism After Major Surgery: A Greater Challenge With Increasing Age

4. Dose-dependent pharmacokinetics of acetaminophen: Evidence of glutathione depletion in humans

5. Can paracetamol (acetaminophen) be administered to patients with liver impairment?

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