TLR4 deficiency upregulates TLR9 expression and enhances irinotecan‐related intestinal mucositis and late‐onset diarrhoea-Reference-Cited by-同舟云学术

TLR4 deficiency upregulates TLR9 expression and enhances irinotecan‐related intestinal mucositis and late‐onset diarrhoea

Published:2021-08 Issue:20 Volume:178 Page:4193-4209
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Wong Deysi Viviana Tenazoa¹²,Holanda Renata Brito Falcão³,Cajado Aurilene Gomes⁴,Bandeira Alessandro Maia⁴,Pereira Jorge Fernando Bessa⁴^ORCID,Amorim Joice Oliveira²,Torres Clarice Sampaio⁴,Ferreira Luana Maria Moura⁴,Lopes Marina Helena Silva¹,Oliveira Roberta Taiane Germano⁵,Pereira Anamaria Falcão⁴,Sant'Ana Rosane Oliveira²⁶,Arruda Larissa Mont'alverne⁶,Ribeiro‐Júnior Howard Lopes⁵,Pinheiro Ronald Feitosa⁵,Almeida Paulo Roberto Carvalho¹,Carvalho Robson Francisco⁷,Chaves Fábio Figueiredo⁶,Rocha‐Filho Duílio Reis⁸,Cunha Fernando Queiroz⁹^ORCID,Lima‐Júnior Roberto César Pereira⁴^ORCID

Affiliation:

1. Graduate Program in Pathology, Department of Pathology and Forensic Medicine, Faculty of Medicine Federal University of Ceará Fortaleza Ceará Brazil

2. Laboratory of Molecular Biology and Genetics, Haroldo Juaçaba Hospital Cancer Institute of Ceará (ICC) Fortaleza Ceará Brazil

3. Graduate Program in Pharmaceutical Sciences, Department of Pharmacy, Faculty of Pharmacy, Nursing and Dentistry Federal University of Ceará Fortaleza Ceará Brazil

4. Laboratory of Inflammation and Cancer Pharmacology, Drug Research and Development Center (NPDM), Department of Physiology and Pharmacology Federal University of Ceará Fortaleza Ceará Brazil

5. Cancer Cytogenomic Laboratory, Drug Research and Development Center (NPDM) Federal University of Ceará Fortaleza Ceará Brazil

6. Clinical Oncology Service, Haroldo Juaçaba Hospital Cancer Institute of Ceará (ICC) Fortaleza Ceará Brazil

7. Department of Structural and Functional Biology Institute of Biosciences, São Paulo State University (UNESP) Botucatu São Paulo Brazil

8. Clinical Oncology Service, Walter Cantídio University Hospital Federal University of Ceará Fortaleza Ceará Brazil

9. Department of Pharmacology, School of Medicine of Ribeirão Preto University of São Paulo São Paulo State of São Paulo Brazil

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.15609

Reference48 articles.

1. THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Catalytic receptors

2. Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology

3. Guidance on the management of diarrhoea during cancer chemotherapy

4. Irinotecan: 25 years of cancer treatment

5. Characterization of a novel mechanism accounting for the adverse cholinergic effects of the anticancer drug irinotecan

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