LAG3 (CD223) as a cancer immunotherapy target

Author:

Andrews Lawrence P.1,Marciscano Ariel E.2,Drake Charles G.3,Vignali Dario A. A.14

Affiliation:

1. Department of Immunology; University of Pittsburgh School of Medicine; Pittsburgh PA USA

2. Department of Radiation Oncology & Molecular Radiation Sciences; Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins School of Medicine; Baltimore MD USA

3. Departments of Oncology, Immunology and Urology; Sidney Kimmel Comprehensive Cancer Center; The Johns Hopkins School of Medicine; Baltimore MD USA

4. Tumor Microenvironment Center; University of Pittsburgh Cancer Institute; Pittsburgh PA USA

Funder

National Institutes of Health

NCI Comprehensive Cancer Center Support CORE

Melanoma Research Association

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference100 articles.

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3. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival;Curiel;Nat Med,2004

4. Regulatory T cells in tumor immunity;Nishikawa;Int J Cancer,2010

5. Breakthrough of the year 2013. Cancer immunotherapy;Couzin-Frankel;Science,2013

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