A single-nucleotide polymorphism in the canine cytochrome b 5 reductase (CYB5R3 ) gene is associated with sulfonamide hypersensitivity and is overrepresented in Doberman Pinschers

Author:

Reinhart J. M.1ORCID,Ekena J.1,Cioffi A. C.1,Trepanier L. A.1

Affiliation:

1. Department of Medical Sciences; School of Veterinary Medicine; University of Wisconsin-Madison; Madison WI USA

Funder

American Kennel Club Canine Health Foundation

National Institutes of Health

Publisher

Wiley

Subject

General Veterinary,Pharmacology

Reference21 articles.

1. Idiosyncratic reactions to sulfonamides in dogs;Cribb;Journal of the American Veterinary Medical Association,1989

2. An in vitro investigation of predisposition to sulphonamide idiosyncratic toxicity in dogs;Cribb;Veterinary Research Communications,1990

3. Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans;Farrell;Journal of Pharmacology and Experimental Therapeutics,2003

4. RNA integrity and the effect on the real-time qRT-PCR performance;Fleige;Molecular Aspects of Medicine,2006

5. Aplastic anemia associated with prolonged high-dose trimethoprim-sulfadiazine administration in two dogs;Fox;Veterinary Clinical Pathology,1993

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