Differences in Parkinson's disease treatment between neurology and other departments in Japan

Author:

Tsuboi Yoshio1,Wada‐Isoe Kenji2,Kondo Hiroyuki3,Kojima Yoshitsugu3,Takeshima Tomomi4ORCID,Iwasaki Kosuke4

Affiliation:

1. Department of Neurology, Faculty of Medicine Fukuoka University Fukuoka Japan

2. Department of Dementia Medicine Kawasaki Medical School Okayama Japan

3. Department of Medical Affairs Otsuka Pharmaceutical Co., Ltd. Tokyo Japan

4. Milliman Inc. Tokyo Japan

Abstract

AbstractBackgroundParkinson's disease is common in elderly people and is treated in the neurology department as well as in other departments. Recently, treatment options for Parkinson's disease have expanded; this complicates selection of the best treatment regimen.AimTo investigate the change in Parkinson's disease treatment in Japan and assess the differences in prescriptions between neurology and other departments.MethodsPatients with Parkinson's disease who were prescribed levodopa and/or non‐ergot dopamine agonist were analyzed in an observational study using a Japanese claims database (April 2008–July 2017). The percentage of patients receiving each antiparkinsonian drug and the proportion of patients prescribed levodopa alone, levodopa plus non‐ergot dopamine agonist, and non‐ergot dopamine agonist alone were calculated by year (2010–2017) and department (neurology or other departments).ResultsWe identified 50,408 patients (mean [standard deviation] age: 73.4 [10.3]), including 25,231 (71.3 [10.1]) and 25,177 (75.5 [10.2]) patients who received their initial Parkinson's disease treatment in neurology and other departments, respectively. The popularity of levodopa alone and levodopa plus non‐ergot‐ dopamine agonist varied in the neurology department, while levodopa alone was the most popular treatment choice in all investigated years in other departments.ConclusionsThe number of patients initially treated for Parkinson's disease in neurology department, relative to other departments, did not differ. The treatment changes were observed in the neurology department but not in other departments.

Funder

Otsuka Pharmaceutical

Publisher

Wiley

Subject

Neurology (clinical),Neurology

Reference29 articles.

1. Development Committee for Parkinson's Disease Treatment [Guideline].Parkinson's disease clinical guideline;2018. Tokyo: Igaku‐Shoin. Japanese.

2. National Institute for Health and Care Excellence [NICE Guideline].Parkinson's disease in adults [NG71];2017. Accessed March 26 2021.https://www.nice.org.uk/guidance/ng71

3. Treatment of Parkinson's disease in Spain

4. Current clinical practice for Parkinson’s disease among Chinese physicians, general neurologists and movement disorders specialists: a national survey

5. Utilization of anti-Parkinson drugs in Australia: 1995-2009

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