Human microRNA hsa-miR-1231 suppresses hepatitis B virus replication by targeting core mRNA

Author:

Kohno T.12,Tsuge M.123,Murakami E.12,Hiraga N.12,Abe H.12,Miki D.124,Imamura M.12,Ochi H.124,Hayes C. N.12,Chayama K.124

Affiliation:

1. Department of Gastroenterology and Metabolism; Applied life sciences; Institute of Biomedical and Health sciences; Hiroshima University; Hiroshima Japan

2. Liver Research Project Center; Hiroshima University; Hiroshima Japan

3. Natural Science Center for Basic Research and Development; Hiroshima University; Hiroshima Japan

4. Laboratory for Liver Diseases; SNP Research Center; The Institute of Physical and Chemical Research (RIKEN); Hiroshima Japan

Funder

Japanese Ministry of Labor and Health and Welfare

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference32 articles.

1. The chimpanzee model: contributions and considerations for studies of hepatitis B virus;Gagneux;Methods Mol Med,2004

2. IFN-alpha inhibits HBV transcription and replication in cell culture and in humanized mice by targeting the epigenetic regulation of the nuclear cccDNA minichromosome;Belloni;J Clin Invest,2012

3. Nuclear HBx binds the HBV minichromosome and modifies the epigenetic regulation of cccDNA function;Belloni;Proc Natl Acad Sci U S A,2009

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