Pre-adapting parasitic phages to a pathogen leads to increased pathogen clearance and lowered resistance evolution with Pseudomonas aeruginosa cystic fibrosis bacterial isolates

Author:

Friman V-P.12,Soanes-Brown D.1,Sierocinski P.13,Molin S.4,Johansen H. K.45,Merabishvili M.678,Pirnay J-P.6,De Vos D.6,Buckling A.1

Affiliation:

1. Biosciences; University of Exeter; Penryn UK

2. Department of Biology; University of York; York UK

3. European Centre for Environment and Human Health in Cornwall; University of Exeter; Penryn UK

4. Department of Systems Biology; Technical University of Denmark; Lyngby Denmark

5. Department of Clinical Microbiology 9301; Rigshospitalet; København Ø Denmark

6. Burn Wound Center; Queen Astrid Military Hospital; Brussel Belgium

7. Research and Development Department; George Eliava Institute of Bacteriophages, Microbiology and Virology; Tbilisi Georgia

8. Laboratory for Bacteriology Research; Faculty of Medicine and Health Sciences; Ghent University; Ghent Belgium

Funder

Wellcome Trust Institutional Strategic Support Fund

Natural Environment Research Council

Biotechnology and Biological Sciences Research Council

AXA Research Fund

Royal Society

MED11

Royal Higher Institute for Defense

Novo Nordisk Foundation

Forskerakademiet

Publisher

Wiley

Subject

Ecology, Evolution, Behavior and Systematics

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