Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition-Reference-Cited by-同舟云学术

Istaroxime stimulates SERCA2a and accelerates calcium cycling in heart failure by relieving phospholamban inhibition

Published:2013-07-26 Issue:8 Volume:169 Page:1849-1861
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Ferrandi Mara¹,Barassi Paolo¹,Tadini-Buoninsegni Francesco²,Bartolommei Gianluca²,Molinari Isabella¹,Tripodi Maria Grazia¹,Reina Cristina¹,Moncelli Maria Rosa²,Bianchi Giuseppe,Ferrari Patrizia¹

Affiliation:

1. Prassis Sigma-Tau Research Institute; Settimo Milanese, Milan; Italy

2. University of Florence; Sesto Fiorentino, Florence; Italy

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12278/fullpdf

Reference45 articles.

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3. Transmembrane helix M6 in sarco(endo)plasmic reticulum Ca(2+)-ATPase forms a functional interaction site with phospholamban. Evidence for physical interactions at other sites;Asahi;J Biol Chem,1999

4. The Ca2+-ATPase (SERCA1) is inhibited by 4-aminoquinoline derivatives through interference with catalytic activation by Ca2+, whereas the ATPase E2 state remains functional;Bartolommei;J Biol Chem,2011

5. Cardiac excitation-contraction coupling;Bers;Nature,2002

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