Fasudil, a rho kinase inhibitor, limits motor neuron loss in experimental models of amyotrophic lateral sclerosis
Author:
Affiliation:
1. Molecular Pharmacology; Department of Biofunctional Evaluation; Gifu Pharmaceutical University; Gifu; Japan
2. Pharmaceuticals Research Center; Asahi Kasei Pharma Corporation; Shizuoka; Japan
Publisher
Wiley
Subject
Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12277/fullpdf
Reference28 articles.
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3. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I;Coleman;Nat Cell Biol,2001
4. Vascular endothelial growth factor counteracts the loss of phospho-Akt preceding motor neurone degeneration in amyotrophic lateral sclerosis;Dewil;Neuropathol Appl Neurobiol,2007
5. The use of transgenic mouse models of amyotrophic lateral sclerosis in preclinical drug studies;Gurney;J Neurol Sci,1997
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