Incidence and prognostic significance of isolated trisomies in adult acute myeloid leukemia: A population-based study from the Swedish AML registry

Author:

Lazarevic Vladimir Lj12ORCID,Rosso Aldana34,Juliusson Gunnar12,Antunovic Petar5,Derolf Åsa Rangert6,Deneberg Stefan6,Möllgård Lars7,Uggla Bertil8,Wennström Lovisa7,Wahlin Anders9,Höglund Martin10,Lehmann Sören10,Johansson Bertil1112

Affiliation:

1. Department of Hematology, Oncology and Radiation Physics; Skåne University Hospital; Lund Sweden

2. Stem Cell Center; Lund University; Lund Sweden

3. Epidemiology and Registry Center in South Sweden; Skåne University Hospital; Lund Sweden

4. Medical Radiology; Department of Translational Medicine; Lund University; Lund Sweden

5. Department of Hematology; Linköping University Hospital; Linköping Sweden

6. Department of Medicine; Division of Hematology; Karolinska University Hospital; Stockholm Sweden

7. Department of Medicine; Sahlgrenska University Hospital; Göteborg Sweden

8. Department of Medicine; School of Health and Medical Sciences; Örebro University Hospital; Örebro Sweden

9. Department of Radiation Sciences; Umeå University; Umeå Sweden

10. Department of Hematology; Academic Hospital; Uppsala Sweden

11. Department of Clinical Genetics; University and Regional Laboratories Region Skåne; Lund Sweden

12. Division of Clinical Genetics; Department of Laboratory Medicine; Lund University; Lund Sweden

Funder

Vetenskapsrådet

Cancerfonden

Regional Cancer Centers

Swedish Association of Local Authorities and Regions (SKL)

Governmental Funding of Clinical Research within the National Health Service

Publisher

Wiley

Subject

Hematology,General Medicine

Reference50 articles.

1. Trisomy 11 in acute myeloid leukemia: ten cases;Bilhou-Nabera;Leukemia,1994

2. Clinical and morphological features of cases of trisomy 13 in acute non-lymphocytic leukemia;Soni;Leukemia,1996

3. Patients with isolated trisomy 8 in acute myeloid leukemia are not cured with cytarabine-based chemotherapy: results from Cancer and Leukemia Group B 8461;Byrd;Clin Cancer Res,1998

4. High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2αβ gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21;Preudhomme;Blood,2000

5. Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461;Farag;Int J Oncol,2002

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