Pathway‐based integration of multi‐omics data reveals lipidomics alterations validated in an Alzheimer's disease mouse model and risk loci carriers

Author:

Garcia‐Segura Monica Emili12,Durainayagam Brenan R.23,Liggi Sonia2ORCID,Graça Gonçalo4,Jimenez Beatriz5,Dehghan Abbas367,Tzoulaki Ioanna3689,Karaman Ibrahim46,Elliott Paul3678,Griffin Julian L.231011ORCID

Affiliation:

1. Department of Brain Sciences Imperial College London London UK

2. Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction Imperial College London London UK

3. UK‐Dementia Research Institute (UK‐DRI) at Imperial College London London UK

4. Section of Bioinformatics, Department of Metabolism, Digestion and Reproduction Imperial College London London UK

5. Section of Bioanalytical Chemistry and the National Phenome Centre, Department of Metabolism, Digestion and Reproduction Imperial College London London UK

6. Department of Epidemiology and Biostatistics Imperial College London London UK

7. MRC Centre for Environment and Health Imperial College London London UK

8. National Institute for Health Research Imperial Biomedical Research Centre Imperial College London UK

9. Department of Hygiene and Epidemiology University of Ioannina Medical School Ioannina Greece

10. Department of Biochemistry and Cambridge Systems Biology Centre University of Cambridge Cambridge UK

11. The Rowett Institute, University of Aberdeen Aberdeen Scotland

Funder

Alzheimer's Society

Medical Research Council Canada

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Biochemistry

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