A single‐domain small protein Med‐ORF10 regulates the production of antitumour agent medermycin in Streptomyces-Reference-Cited by-同舟云学术

A single‐domain small protein Med‐ORF10 regulates the production of antitumour agent medermycin in Streptomyces

Published:2021-06-17 Issue:5 Volume:14 Page:1918-1930
ISSN:1751-7915
Container-title:Microbial Biotechnology
language:en
Short-container-title:Microb. Biotechnol.

Author:

Cai Xiaofeng¹²³,Li Caiyun¹,Ichinose Koji⁴,Jiang Yali²,Liu Ming²,Wang Huili²,Gong Caixia²,Li Le²,Wan Juan²,Zhao Yiming¹,Yang Qing⁵,Li Aiying¹²^ORCID

Affiliation:

1. Helmholtz International Lab for Anti‐Infectives Shandong University‐Helmholtz Institute of Biotechnology State Key Laboratory of Microbial Technology Shandong University Qingdao 266237 China

2. The College of Life Sciences Key Laboratory of Pesticide and Chemical Biology Ministry of Education Central China Normal University Wuhan 430079 China

3. School of Pharmacy Huazhong University of Science and Technology Wuhan 430030 China

4. Research Institute of Pharmaceutical Sciences Musashino University Tokyo 202‐8585 Japan

5. State Key Laboratory of Genetic Engineering School of Life Sciences Fudan University Songhu Road 2005 Shanghai 200438 China

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Higher Education Discipline Innovation Project

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Biochemistry,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/1751-7915.13834

Reference35 articles.

1. Recombineering for Genetic Engineering of Natural Product Biosynthetic Pathways

2. SnoaW/SnoaL2: A Different Two-Component Monooxygenase

3. Crystal Structures of SnoaL2 and AclR: Two Putative Hydroxylases in the Biosynthesis of Aromatic Polyketide Antibiotics

4. Cloning, sequencing and deduced functions of a cluster of Streptomyces genes probably encoding biosynthesis of the polyketide antibiotic frenolicin

5. Practical procedures for genetic manipulation systems for medermycin‐producing Streptomyces sp. AM‐7161;Deng H.;J Basic Microbiol,2010

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