Scale-up/Scale-down of microbial bioprocesses: a modern light on an old issue
Author:
Affiliation:
1. TERRA Research Center; Microbial Processes and Interactions (MiPI); University of Liège; Liège Belgium
2. DSM Biotechnology Center; Delft The Netherlands
3. Department of Biotechnology; Technical University Delft; Delft The Netherlands
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Biochemistry,Bioengineering,Biotechnology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/1751-7915.12732/fullpdf
Reference12 articles.
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2. A methodology for the design of scale-down bioreactors by the use of mixing and circulation stochastic models;Delvigne;Biochem Eng J,2006
3. Metabolic variability in bioprocessing: implications of microbial phenotypic heterogeneity;Delvigne;Trends Biotechnol,2014
4. Euler-Lagrange analysis towards representative down-scaling of a 22 m3 aerobic S. cerevisiae fermentation;Haringa;Chem Eng Sci,2017
5. Modeling the dynamics of E. coli populations in the three-dimensional turbulent field of a stirred bioreactor - A structured-segregated approach;Lapin;Chem Eng Sci,2006
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