A perspective current and past modes of inhalation therapy

Author:

Canto Mangana José12,Schilder Kelsey Aguirre1,Bretones‐Pedrinaci José Ignacio2ORCID,Blesa Ana Rosa Márquez1,de Medina Fermín Sánchez345,Martínez‐Augustin Olga1456,Daddaoua Abdelali156ORCID

Affiliation:

1. Department of Biochemistry and Molecular Biology II, Pharmacy School University of Granada Granada Spain

2. Pharmacy Services A.S. Hospital de Poniente de Almería Almería Spain

3. Department of Pharmacology, School of Pharmacy University of Granada Granada Spain

4. Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) Madrid Spain

5. Instituto de Investigación Biosanitaria (IBS) Granada Spain

6. Institute of Nutrition and Food Technology ‘José Mataix’, Center of Biomedical Research University of Granada Granada Spain

Abstract

AbstractInhalation is the preferred route of delivery for anti‐asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects. Therefore, the current brief covers an interesting collection of inhaler action modes, shedding light on their molecular mechanisms and clinical applications for anti‐asthma, COPD and antibacterial inhalation therapy. Hence, not only enriches our understanding of inhalation therapy molecular intricacies but also provides a comprehensive overview of the evolving landscape in clinical and antibacterial inhalation therapy. In doing so, it underscores the pivotal role of microbiology and biotechnology in advancing therapeutic approaches that harness the power of inhalation.

Publisher

Wiley

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