Protective Effect of Dermal Brimonidine Applications Against UV Radiation-induced Skin Tumors, Epidermal Hyperplasia and Cell Proliferation in the Skin of Hairless Mice

Author:

Bouvier Guy1,Learn Douglas B.2,Nonne Christelle1,Feraille Gérard1,Vial Emmanuel1,Ruty Bernard1

Affiliation:

1. Galderma R&D; Sophia-Antipolis France

2. Charles River Laboratories Preclinical Services; Horsham PA

Funder

Galderma R&D

Charles River Laboratories

Publisher

Wiley

Subject

Physical and Theoretical Chemistry,General Medicine,Biochemistry

Reference25 articles.

1. Brimonidine. A review of its pharmacological properties and clinical potential in the management of open-angle glaucoma and ocular hypertension;Adkins;Drugs Aging,1998

2. Preclinical evaluation of Brimonidine;Burke;Surv. Ophthalmol.,1996

3. Preclinical safety profile of brimonidine;Angelov;Eur. J. Ophthalmol.,1996

4. A review of the genotoxicity of marketed pharmaceuticals;Snyder;Mutat. Res.,2001

5. Reproductive and development safety studies with brimonidine (AlphaganTM) [abstract];Angelov;Invest. Ophthalmol. Vis. Sci.,1996

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