Potential limits of AAV-based gene therapy with the use of new transgenes expressing factor IX fusion proteins
Author:
Affiliation:
1. EA 4609-Hémostase et Cancer; Université Claude Bernard Lyon I; Lyon France
2. Laboratoire D’hématologie; Hospices Civils de Lyon; Lyon France
3. Research Department of Haematology; University of London Cancer Institute; London UK
Funder
Fondation Groupama pour la Santé - Vaincre les maladies Rares
Publisher
Wiley
Subject
Genetics(clinical),Hematology,General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/hae.13651/fullpdf
Reference33 articles.
1. Genetic fusion to albumin improves the pharmacokinetic properties of factor IX;Metzner;Thromb Haemost,2009
2. Prolonged activity of factor IX as a monomeric Fc fusion protein;Peters;Blood,2010
3. Long-acting recombinant coagulation factor IX albumin fusion protein (rIX-FP) in hemophilia B: results of a phase 3 trial;Santagostino;Blood,2016
4. Phase 3 study of recombinant factor IX Fc fusion protein in hemophilia B;Powell;N Engl J Med,2013
5. The major histocompatibility complex-related Fc receptor for IgG (FcRn) binds albumin and prolongs its lifespan;Chaudhury;J Exp Med,2003
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Half-Life Extension Enhances Drug Efficacy in Adeno-Associated Virus Delivered Gene Therapy;Engineering;2023-02
2. Gene Therapy For Hemophilia B Using CB 2679d-GT: A Novel Factor IX Variant With Higher Potency Than Factor IX Padua;Blood;2021-03-18
3. Protein-Engineered Coagulation Factors for Hemophilia Gene Therapy;Molecular Therapy - Methods & Clinical Development;2019-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3