Heart transplantation for pediatric foreign nationals in the United States-Reference-Cited by-同舟云学术

Heart transplantation for pediatric foreign nationals in the United States

Published:2023-01-11 Issue:2 Volume:37 Page:
ISSN:0902-0063
Container-title:Clinical Transplantation
language:en
Short-container-title:Clinical Transplantation

Author:

Harano Takashi¹^ORCID,Sheth Megha²,Sasaki Kazunari³,Yu Jeremy⁴,Wightman Sean C.¹,Atay Scott M.¹,Sainathan Sandeep⁵,Kim Anthony W.¹

Affiliation:

1. Division of Thoracic Surgery Department of Surgery Keck School of Medicine of the University of Southern California Los Angeles California USA

2. Keck School of Medicine of the University of Southern California Los Angeles California USA

3. Division of Abdominal Transplant Department of Surgery Stanford University Palo Alto California USA

4. Department of Psychiatry and Behavioral Sciences & SC CTSI Biostatistics, Epidemiology, and Research Design Keck School of Medicine of the University of Southern California Los Angeles California USA

5. Division of Cardiothoracic Surgery Department of Surgery University of Miami, Miller School of Medicine and Jackson Memorial Hospital Miami Florida USA

Abstract

AbstractBackgroundThis study aimed to clarify survival outcomes, waitlist mortality, and waitlist days of heart transplantation of pediatric foreign nationals compared to pediatric United States (US) citizens.MethodsWe retrieved data from March 2012 to June 2021 in the United Network Organ Sharing (UNOS) registry.ResultsOf 5857 pediatric patients newly waitlisted, 133 (2.27%) patients were non‐US citizen/non‐US residents (non‐citizen non‐resident [NCNR]). Patients with congenital heart disease were higher in the US citizen group than in the NCNR group (51.9% vs. 22.6%, p < .001); 76.7% of patients in the NCNR group (102/133) had cardiomyopathy. Of the 133 NCNRs, 111 patients (83.5%) underwent heart transplantation, which was significantly higher than that in the US citizen group (68.6%, p < .001). The median waitlist time was 71 days (IQR, 22–172 days) in the NCNR group and 74 days (29–184 days) in the US citizen group (p = .48). Survival after heart transplant was significantly better in the NCNR group than in the US citizen group (n = 3982; logrank test p = .015).ConclusionsHeart transplantation for pediatric foreign nationals was mostly indicated for cardiomyopathy, and their transplant rate was significantly higher than that in the US citizen group, with better survival outcomes. The better survival outcomes in the NCNR group compared to the US citizen group can likely be attributed to the differing diagnoses for which transplantation was performed.

Publisher

Wiley

Subject

Transplantation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/ctr.14900

Reference16 articles.

1. Organ Procurement and Transplantation Network. Published 2022. Accessed June 25 2022.https://optn.transplant.hrsa.gov/media/eavh5bf3/optn_policies.pdf

2. Organ trafficking and transplant tourism and commercialism: the Declaration of Istanbul

3. Transplantation in foreign nationals: Lower rates of waitlist mortality and higher rates of lost to follow-up posttransplant

4. POINT: Should US Centers Transplant Solid Organs Into International Recipients? Yes

5. COUNTERPOINT: Should US Centers Transplant Solid Organs Into International Recipients? No