p53‐dependent up‐regulation of CDKN 1A and down‐regulation of CCNE 2 in response to beryllium
Author:
Affiliation:
1. Department of Chemistry and Biochemistry University of Nevada Las Vegas Las Vegas NV USA
2. Department of Clinical Neurosciences University of Calgary Calgary AB Canada
Funder
National Institutes of Health
Army Research Office
University of Nevada, Las Vegas
Publisher
Wiley
Subject
Cell Biology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cpr.12291
Reference51 articles.
1. Specific G1-S phase cell cycle block by beryllium as demonstrated by cytofluorometric analysis
2. Inhibition of normal human lung fibroblast growth by beryllium
3. Beryllium Induces Premature Senescence in Human Fibroblasts
4. Beryllium sulfate induces p21 CDKN1A expression and a senescence-like cell cycle arrest in susceptible cancer cell types
5. p21 is a universal inhibitor of cyclin kinases
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