Clinical and regulatory implications of active run-in phases in long-term studies for bipolar disorder

Author:

Cipriani A.12,Barbui C.2,Rendell J.1,Geddes J. R.1

Affiliation:

1. Department of Psychiatry; University of Oxford; Oxford UK

2. Department of Public Health and Community Medicine; Section of Psychiatry; University of Verona; Verona Italy

Publisher

Wiley

Subject

Psychiatry and Mental health

Reference29 articles.

1. A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder;Soares-Weiser;Health Technol Assess,2007

2. National Institute for Health and Clinical Excellence (NICE) Bipolar disorder: the management of bipolar disorder in adults, children and adolescents, in primary and secondary care www.nice.org.uk/CG038

3. Pharmacological approaches in bipolar disorders and the impact on cognition: a critical overview;Dias;Acta Psychiatr Scand,2012

4. What is a run-in phase?;Cipriani;Epidemiol Psichiatr Soc,2010

5. Run-in periods in randomized trials: implications for the application of results in clinical practice;Pablos-Méndez;JAMA,1998

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