The first Australian uterus transplantation procedure: A result of a long‐term Australian‐Swedish research collaboration

Author:

Deans Rebecca12ORCID,Pittman Jana12ORCID,Gerstl Brigitte2ORCID,Haghighi Koroush23,Pleass Henry45,KÄhler Pernilla Dahm67,Kvarnström Niclas7,Hseuh Wayne12,Keung Karen3,Luxton Grant3,Yong Kenneth3,Caldas Rita1,Byun Lily1,Loo Christine38,Tippett John1,Caponas George1,Moses Daniel23,Wan King‐Man12,Arulpragasam Kaushalya12,Kiely Neill1,Brännström Mats67,Abbott Jason12ORCID

Affiliation:

1. Department of Gynaecology Royal Hospital for Women New South Wales Sydney Australia

2. Department of Gynaecology University of New South Wales New South Wales Sydney Australia

3. Department of Gynaecology Prince of Wales Hospital New South Wales Sydney Australia

4. Department of Gynaecology Westmead Hospital New South Wales Sydney Australia

5. Department of Gynaecology Sydney University New South Wales Sydney Australia

6. Department of Obstetrics and Gynaecology Sahlgrenska Academy Gothenburg Sweden

7. The Faculty of Medicine University of Gothenburg Sweden Gothenburg Sweden

8. Department of Clinical Pathology South‐Eastern Area Laboratory Services New South Wales Sydney Australia

Abstract

AimsThe aim is to report the results of Australia's first uterus transplantation (UTx).MethodsFollowing long‐standing collaboration between the Swedish and Australian teams, Human Research Ethics approval was obtained to perform six UTx procedures in a collaborative multi‐site research study (Western Sydney Local District Health 2019/ETH13038), including Royal Hospital for Women, Prince of Wales Hospital, and Westmead Hospital in New Souh Wales. Surgeries were approved in both the live donor (LD) and deceased donor models in collaboration with the inaugural Swedish UTx team.ResultsThis is the first UTx procedure to occur in Australia, involving a mother donating her uterus to her daughter. The total operative time for the donor was 9 h 54 min. Concurrently, recipient surgery was synchronised to minimise graft ischaemic time, and the total operative time for the recipient was 6 h 12 min. Surgery was by laparotomy in the LD and recipient. The total warm ischaemic time of the graft was 1 h 53 min, and the cold ischaemic time was 2 h 17 min (total ischaemic time 4 h 10 min). The patient's first menstruation occurred 33 days after the UTx procedure.ConclusionTwenty‐five years of Swedish and Australian collaboration has led to Australia's first successfully performed UTx surgery at The Royal Hospital for Women, Sydney, Australia.

Publisher

Wiley

Subject

Obstetrics and Gynecology,General Medicine

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Living-Donor Uterus Transplantation: A Clinical Review;Journal of Clinical Medicine;2024-01-29

2. Miracles of science: Birth after uterus transplantation;Journal of Obstetrics and Gynaecology Research;2023-11-03

3. Deceased donor availability for uterus transplantation in Australia;Australian and New Zealand Journal of Obstetrics and Gynaecology;2023-07-03

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