1. Department of Electrical Engineering and Electronics; University of Liverpool; L69 3GJ UK
2. Department of Molecular and Clinical Pharmacology; University of Liverpool; L69 3GL UK
3. Department of Computer Science; University of Liverpool; L69 3BX UK
4. Royal Liverpool and Broadgreen University Hospital NHS Trust; Liverpool L7 8XP UK
5. Drug Safety & Epidemiology; Novartis Pharma AG, Postfach; CH-4002 Basel Switzerland