Biological characterization of new inhibitors of microsomal PGE synthase‐1 in preclinical models of inflammation and vascular tone

Author:

Larsson Karin1,Steinmetz Julia1,Bergqvist Filip1ORCID,Arefin Samsul2,Spahiu Linda3,Wannberg Johan4,Pawelzik Sven‐Christian15,Morgenstern Ralf3,Stenberg Patric6,Kublickiene Karolina2,Korotkova Marina1,Jakobsson Per‐Johan1

Affiliation:

1. Rheumatology Unit, Department of Medicine, Solna, Karolinska InstitutetKarolinska University Hospital Stockholm Sweden

2. Division of Renal Medicine, Department of Clinical Science, Intervention and Technology, Karolinska InstitutetKarolinska University Hospital Stockholm Sweden

3. Biochemical Toxicology Unit, Institute of Environmental MedicineKarolinska Institutet Stockholm Sweden

4. SciLifeLab Drug Discovery and Development Platform, Medicinal Chemistry—Lead Identification, Department of Medicinal ChemistryUppsala University Uppsala Sweden

5. Theme Heart and Vessels, Division of Valvular and Coronary DiseasesKarolinska University Hospital Stockholm Sweden

6. Gesynta Pharma AB Solna Sweden

Funder

Innovative Medicines Initiative

Karolinska Institutet

Vetenskapsrådet

VINNOVA

Stockholms Läns Landsting

Cancerföreningen i Stockholm

Cancerfonden

Barncancerfonden

Stiftelsen Konung Gustaf V:s 80-årsfond

Reumatikerförbundet

Publisher

Wiley

Subject

Pharmacology

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