Development of an FhbB based chimeric vaccinogen that elicits antibodies that block Factor H binding and cleavage by the periopathogen Treponema denticola-Reference-Cited by-同舟云学术

Development of an FhbB based chimeric vaccinogen that elicits antibodies that block Factor H binding and cleavage by the periopathogen Treponema denticola

Published:2020-12-09 Issue:1 Volume:36 Page:50-57
ISSN:2041-1006
Container-title:Molecular Oral Microbiology
language:en
Short-container-title:Mol Oral Microbiol

Author:

O'Bier Nathaniel S.¹,Patel Dhara T.¹,Oliver Lee D.¹,Miller Daniel P.¹,Marconi Richard T.¹^ORCID

Affiliation:

1. Department Microbiology and Immunology Virginia Commonwealth University Medical Center Richmond VA USA

Publisher

Wiley

Subject

Microbiology (medical),General Dentistry,Immunology,Microbiology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/omi.12325

Reference35 articles.

1. A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine

2. A Meningococcal Factor H Binding Protein Mutant That Eliminates Factor H Binding Enhances Protective Antibody Responses to Vaccination

3. The Effect of Human Factor H on Immunogenicity of Meningococcal Native Outer Membrane Vesicle Vaccines with Over-Expressed Factor H Binding Protein

4. MenB-FHbp Vaccine Protects Against Diverse Meningococcal Strains in Adolescents and Young Adults: Post Hoc Analysis of Two Phase 3 Studies

5. Sex, Age, and Race Effects on Immunogenicity of MenB-FHbp, A Bivalent Meningococcal B Vaccine: Pooled Evaluation of Clinical Trial Data

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