Alisporivir with peginterferon/ribavirin in patients with chronic hepatitis C genotype 1 infection who failed to respond to or relapsed after prior interferon-based therapy: FUNDAMENTAL, a Phase II trial

Author:

Buti M.1,Flisiak R.2,Kao J.-H.3,Chuang W.-L.4,Streinu-Cercel A.5,Tabak F.6,Calistru P.7,Goeser T.8,Rasenack J.9,Horban A.10,Davis G. L.11,Alberti A.12,Mazzella G.13,Pol S.14,Orsenigo R.15,Brass C.15

Affiliation:

1. Liver Unit; Hospital Universitario Valle Hebron and Ciberehd del Instituto Carlos III; Barcelona Spain

2. Department of Infectious Diseases and Hepatology; Medical University of Bialystok; Bialystok Poland

3. National Taiwan University Hospital; Taipei Taiwan

4. Kaohsiung Medical University Hospital; Kaohsiung Medical University; Kaohsiung Taiwan

5. Carol Davila University of Medicine and Pharmacy, and National Institute for Infectious Diseases ‘Prof. Dr. Matei Balş’; Bucharest Romania

6. Istanbul University Cerrahpasa Medical School; Istanbul Turkey

7. Centrul de Diagnostic si Tratament Dr. Viktor Babeş; Bucharest Romania

8. Klinik für Gastroenterologie und Hepatologie Universitätsklinik Köln; Köln Germany

9. Universitätsklinik Albert-Ludwigs Universität Freiburg; Freiburg Germany

10. Warsaw Medical University and Hospital of Infectious Disease; Warsaw Poland

11. Baylor University Medical Center; Dallas TX USA

12. Department of Molecular Medicine; University of Padova; Padova Italy

13. Azienda Ospedaliera di Bologna Policl; S. Orsola-Malpighi Hospital; Bologna Italy

14. Hôpital Cochin; Paris France

15. Novartis Pharma AG; Basel Switzerland

Funder

Novartis

Publisher

Wiley

Subject

Virology,Infectious Diseases,Hepatology

Reference27 articles.

1. World Health Organization Hepatitis C. Fact sheet N°164; April 2014 http://www.who.int/mediacentre/factsheets/fs164/en/

2. Hepatitis C virus therapy update 2013;Casey;Curr Opin Gastroenterol,2013

3. Current and future therapies for hepatitis C virus infection;Laing;N Engl J Med,2013

4. Hepatitis C in the interferon-free era;Streinu-Cercel;Germs,2013

5. Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial;Manns;Lancet,2001

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