Regulation of autoimmune and anti-tumour T-cell responses by PTPN22
Author:
Affiliation:
1. Leeds Institute of Cancer and Pathology; St James's University Hospital; University of Leeds; Leeds UK
2. Ashworth Laboratories; Institute of Immunology and Infection Research; University of Edinburgh; Edinburgh UK
Funder
Cancer Research UK
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/imm.12919/fullpdf
Reference64 articles.
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2. CTLA4 gene polymorphism and autoimmunity;Gough;Immunol Rev,2005
3. Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease;Bottini;Annu Rev Immunol,2014
4. The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans;Menard;J Clin Invest,2011
5. PTPN22 inhibition resets defective human central B cell tolerance;Schickel;Sci Immunol,2016
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