The added values of multiplex reverse transcriptase-PCR followed by mutation screening in the initial evaluation of acute leukemia

Author:

Kim B.1,Cho Y.-U.1,Bae M.-H.1,Jang S.1,Seo E.-J.1,Chi H.-S.1,Park C.-J.1

Affiliation:

1. Department of Laboratory Medicine; University of Ulsan; College of Medicine and Asan Medical Center; Seoul Korea

Publisher

Wiley

Subject

Biochemistry, medical,Clinical Biochemistry,Hematology,General Medicine

Reference31 articles.

1. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials;Grimwade;Blood,2010

2. Prospective application of a multiplex reverse transcription-polymerase chain reaction assay for the detection of balanced translocations in leukaemia: a single-laboratory study of 390 paediatric and adult patients;Olesen;Br J Haematol,2004

3. Multiplex reverse transcription polymerase chain reaction screening in acute myeloid leukemia detects cytogenetically unrevealed abnormalities of prognostic significance;Hutchings Hoffmann;Haematologica,2005

4. Comparison of multiplex reverse transcription polymerase chain reaction and conventional cytogenetics as a diagnostic strategy for acute leukemia;Park;Int J Lab Hematol,2008

5. Diagnostic utility of a multiplex RT-PCR assay in detecting fusion transcripts from recurrent genetic abnormalities of acute leukemia by WHO 2008 classification;Song;Diagn Mol Pathol,2012

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