Increased baseline RUNX2 , caspase 3 and p21 gene expressions in the peripheral blood of disease-modifying anti-rheumatic drug-naïve rheumatoid arthritis patients are associated with improved clinical response to methotrexate therapy

Author:

Tchetina Elena V.1ORCID,Demidova Natalia V.2,Markova Galina A.1,Taskina Elena A.3,Glukhova Svetlana I.4,Karateev Dmitry E.2

Affiliation:

1. Immunology & Molecular Biology Laboratory; Nasonova Research Institute of Rheumatology; Moscow Russia

2. Early Rheumatoid Arthritis Department; Nasonova Research Institute of Rheumatology; Moscow Russia

3. Osteoarthritis Laboratory; Nasonova Research Institute of Rheumatology; Moscow Russia

4. Statistics Department; Nasonova Research Institute of Rheumatology; Moscow Russia

Funder

Russian Foundation for Basic Research

Publisher

Wiley

Subject

Rheumatology

Reference51 articles.

1. Rheumatoid Arthritis: pathophysiology and implications for therapy;Harris;N Engl J Med,1990

2. Efficacy of methotrexate in rheumatoid arthritis;Weinblatt;Br J Rheumatol,1995

3. Efficacy and toxicity of methotrexate (MTX) monotherapy versus MTX combination therapy with non-biological disease-modifying antirheumatic drugs in rheumatoid arthritis: a systematic review and meta-analysis;Katchamart;Ann Rheum Dis,2009

4. Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?;Romão;BMC Med,2013

5. Increased type II collagen degradation and very early focal cartilage degeneration is associated with upregulation of chondrocyte differentiation related genes in early human articular cartilage lesions;Tchetina;J Rheumatol,2005

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3